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Lipostar

Lipostar is the latest software from Molecular Discovery, developed to assist LC/MS-based lipidomics from the very beginning (direct import of raw data files) to the final goal (lipid identification, statistical analysis, report generation).

Lipostar_logo

Due to its versatility, Lipostar finds application either in untargeted, semi-targeted or targeted lipidomics, and dedicated workflows have been also developed to assist flux analysis when stable isotope labeling experiments are performed. During a Lipostar session, the user can also combine different modes of lipidomics analysis, to increase the knowledge and obtain a more comprehensive analysis of lipid profiles.

Key features include automatic lipid identification (with or without the use of a lipid fragment database) and an ultimate module for statistical analysis, designed to be user-friendly for beginners as well as exhaustive for advanced users.

Features

  • Fast and intuitive filters to pick lipids in complex mixtures
  • Reliable sample alignment, with algorithms to get rid of the batch effect
  • Fully automatized procedure for prediction in statistical analysis: build your model and project new samples in a single click (from raw data to projection plot).
  • Module (the DB Manager) to build customized databases of fragmented lipids, including stable isotope-labeled species.
  • Automatic lipid identification, with or without the use of a lipid fragment database.
  • Automatic report generation

References

Goracci L; Tortorella S; Tiberi P; Pellegrino RM; Di Veroli A; Valeri A; Cruciani G,
Lipostar, a Comprehensive Platform-Neutral Cheminformatics Tool for Lipidomics.
Anal. Chem., 2017, 89 (11), pp 6257–6264